• Target：
• GPR48

• Fields：
• >>Wnt signaling pathway

• Gene Name：
• LGR4

• Protein Name：
• Leucine-rich repeat-containing G-protein coupled receptor 4

• Human Gene Id：
• 55366

• Human Swiss Prot No：
• Q9BXB1

• Mouse Swiss Prot No：
• A2ARI4

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human LGR4. AA range:461-510

• Specificity：
• GPR48 Polyclonal Antibody detects endogenous levels of GPR48 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• LGR4;GPR48;Leucine-rich repeat-containing G-protein coupled receptor 4;G-protein coupled receptor 48

• Observed Band(KD)：
• 100kD

• Background：
• The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016],

• Function：
• function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 15 LRR (leucine-rich) repeats.,tissue specificity:Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.

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