• Target：
• GPR41

• Gene Name：
• FFAR3

• Protein Name：
• Free fatty acid receptor 3

• Human Gene Id：
• 2865

• Human Swiss Prot No：
• O14843

• Mouse Gene Id：
• 233080

• Mouse Swiss Prot No：
• Q3UFD7

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human FFAR3. AA range:11-60

• Specificity：
• GPR41 Polyclonal Antibody detects endogenous levels of GPR41 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• FFAR3;GPR41;Free fatty acid receptor 3;G-protein coupled receptor 41

• Observed Band(KD)：
• 38kD

• Background：
• function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest level in adipose tissue, and lower expression across all tissues tested.,

• Function：
• function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest level in adipose tissue, and lower expression across all tissues tested.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Highest level in adipose tissue, and lower expression across all tissues tested. Expressed in sympathetic ganglia.

Bifidobacterium animalis subsp. lactis A6 Enhances Fatty Acid β-Oxidation of Adipose Tissue to Ameliorate the Development of Obesity in Mice Nutrients. 2022 Jan;14(3):598. WB Mouse epididymal adipose tissues

Gut microbiota modulate CD8+ T cell immunity in gastric cancer through Butyrate/GPR109A/HOPX Gut Microbes Xiang Yu WB Human 1:1000 GES-1 cell,MGC-803 cell,HGC-27 cell,SNU-216 cell

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