• Target：
• GPR133

• Gene Name：
• GPR133

• Protein Name：
• Probable G-protein coupled receptor 133

• Human Gene Id：
• 283383

• Human Swiss Prot No：
• Q6QNK2

• Mouse Swiss Prot No：
• Q80T32

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GPR133. AA range:461-510

• Specificity：
• GPR133 Polyclonal Antibody detects endogenous levels of GPR133 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GPR133;PGR25;Probable G-protein coupled receptor 133;G-protein coupled receptor PGR25

• Observed Band(KD)：
• 96kD

• Background：
• The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010],

• Function：
• function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Up-regulated in CD133(+) cell population of glioblastoma.

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