• Target：
• GPR124

• Gene Name：
• GPR124

• Protein Name：
• G-protein coupled receptor 124

• Human Gene Id：
• 25960

• Human Swiss Prot No：
• Q96PE1

• Mouse Gene Id：
• 78560

• Mouse Swiss Prot No：
• Q91ZV8

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GPR124. AA range:1151-1200

• Specificity：
• GPR124 Polyclonal Antibody detects endogenous levels of GPR124 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GPR124;KIAA1531;TEM5;G-protein coupled receptor 124;Tumor endothelial marker 5

• Observed Band(KD)：
• 145kD

• Background：
• caution:It is uncertain whether Met-1 or Met-8 is the initiator.,domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,tissue specificity:Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.,

• Function：
• caution:It is uncertain whether Met-1 or Met-8 is the initiator.,domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,tissue specificity:Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein . Cell projection, filopodium . Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact. .

• Expression：
• Expressed in endothelial cells (at protein level) (PubMed:15021905, PubMed:16982628). Abundantly expressed in heart, placenta, ovary, small intestine, and colon (PubMed:15021905).

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