• Target：
• Glucagon Receptor

• Fields：
• >>Neuroactive ligand-receptor interaction;>>Glucagon signaling pathway

• Gene Name：
• GCGR

• Protein Name：
• Glucagon receptor

• Human Gene Id：
• 2642

• Human Swiss Prot No：
• P47871

• Mouse Gene Id：
• 14527

• Mouse Swiss Prot No：
• Q61606

• Rat Gene Id：
• 24953

• Rat Swiss Prot No：
• P30082

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GLR. AA range:95-144

• Specificity：
• Glucagon Receptor Polyclonal Antibody detects endogenous levels of Glucagon Receptor protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GCGR;Glucagon receptor;GL-R

• Observed Band(KD)：
• 54kD

• Background：
• glucagon receptor(GCGR) Homo sapiens The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010],

• Function：
• disease:It is a candidate for certain defects in non-insulin-dependent diabetes mellitus (NIDDM). The variant in position 40 (Ser) is found in some NIDDM patients, but also in nondiabetic subjects.,function:This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 2 family.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein . Is rapidly internalized after ligand-binding. .

• Expression：
• Liver,Placenta,

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs