GIMAP4 Polyclonal Antibody

    • Catalog No.:YT1904
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • GIMAP4
      • Gene Name:
      • GIMAP4
      • Protein Name:
      • GTPase IMAP family member 4
      • Human Swiss Prot No:
      • Q9NUV9
      • Mouse Swiss Prot No:
      • Q99JY3
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human GIMAP4. AA range:131-180
      • Specificity:
      • GIMAP4 Polyclonal Antibody detects endogenous levels of GIMAP4 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • GIMAP4;IAN1;IMAP4;MSTP062;GTPase IMAP family member 4;Immunity-associated nucleotide 1 protein;IAN-1;hIAN1;Immunity-associated protein 4
      • Observed Band(KD):
      • 38kD
      • Background:
      • This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.,similarity:Belongs to the IAN GTP-binding protein family.,tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.,
      • Subcellular Location:
      • Cytoplasm, cytosol .
      • Expression:
      • Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
      • Products Images
      • Western Blot analysis of various cells using GIMAP4 Polyclonal Antibody
      • Western blot analysis of lysates from HeLa, HT-29, and RAW264.7 cells, using GIMAP4 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from COLO205 cells using GIMAP4 antibody.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).