• Target：
• GBDR1

• Gene Name：
• UBAC1

• Protein Name：
• Ubiquitin-associated domain-containing protein 1

• Human Gene Id：
• 10422

• Human Swiss Prot No：
• Q9BSL1

• Mouse Swiss Prot No：
• Q8VDI7

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140

• Specificity：
• GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• UBAC1;GBDR1;KPC2;UBADC1;Ubiquitin-associated domain-containing protein 1;UBA domain-containing protein 1;E3 ubiquitin-protein ligase subunit KPC2;Glialblastoma cell differentiation-related protein 1;Kip1 ubiquitination-promoting com

• Observed Band(KD)：
• 45kD

• Background：
• function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,

• Function：
• function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Ubiquitous.

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