Gasdermin C Polyclonal Antibody

    • Catalog No.:YT1855
    • Applications:WB IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • Gasdermin C
      • Gene Name:
      • GSDMC
      • Protein Name:
      • Gasdermin-C
      • Human Swiss Prot No:
      • Q9BYG8
      • Mouse Swiss Prot No:
      • Q99NB5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human GSDMC. AA range:109-158
      • Specificity:
      • Gasdermin C Polyclonal Antibody detects endogenous levels of Gasdermin C protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • GSDMC;MLZE;Gasdermin-C;Melanoma-derived leucine zipper-containing extranuclear factor
      • Observed Band(KD):
      • 55kD
      • Background:
      • caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen.,
      • Function:
      • caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen.,
      • Subcellular Location:
      • [Gasdermin-C]: Cytoplasm, cytosol .; [Gasdermin-C, N-terminal]: Cell membrane ; Multi-pass membrane protein .
      • Expression:
      • Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310).
      • Products Images
      • Immunofluorescence analysis of A549. 1,primary Antibody was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 488 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
      • Western Blot analysis of various cells using Gasdermin C Polyclonal Antibody diluted at 1:500
      • Western blot analysis of GSDMC Antibody. The lane on the right is blocked with the GSDMC peptide.
      • Western blot analysis of the lysates from HepG2 cells using GSDMC antibody.