• Target：
• GALR1

• Fields：
• >>Neuroactive ligand-receptor interaction

• Gene Name：
• GALR1

• Protein Name：
• Galanin receptor type 1

• Human Gene Id：
• 2587

• Human Swiss Prot No：
• P47211

• Mouse Gene Id：
• 14427

• Mouse Swiss Prot No：
• P56479

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210

• Specificity：
• GALR1 Polyclonal Antibody detects endogenous levels of GALR1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GALR1;GALNR;GALNR1;Galanin receptor type 1;GAL1-R;GALR-1

• Molecular Weight(Da)：
• 39kD

• Background：
• The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],

• Function：
• function:Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,PTM:Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Brain,Melanoma,Small intestine,

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