FOSL2 Polyclonal Antibody
- Catalog No.:YT1739
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- FOSL2
- Fields:
- >>Osteoclast differentiation
- Gene Name:
- FOSL2
- Protein Name:
- Fos-related antigen 2
- Human Gene Id:
- 2355
- Human Swiss Prot No:
- P15408
- Mouse Gene Id:
- 14284
- Mouse Swiss Prot No:
- P47930
- Rat Gene Id:
- 25446
- Rat Swiss Prot No:
- P51145
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Fra-2. AA range:271-320
- Specificity:
- FOSL2 Polyclonal Antibody detects endogenous levels of FOSL2 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- FOSL2;FRA2;Fos-related antigen 2;FRA-2
- Observed Band(KD):
- 43kD
- Background:
- The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2014],
- Function:
- similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,
- Subcellular Location:
- Nucleus .
- Expression:
- Endothelial cell,Epithelium,Lung,
Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL28. Chuanxin Wang Mouse 1:50 pancreas tissue
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- Antibody-FAQs
- Products Images
- Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL28. Chuanxin Wang Mouse 1:50 pancreas tissue
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Fra-2 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from LOVO cells, using Fra-2 Antibody. The lane on the right is blocked with the synthesized peptide.