• Target：
• FKBPL

• Gene Name：
• FKBPL

• Protein Name：
• FK506-binding protein-like

• Human Gene Id：
• 63943

• Human Swiss Prot No：
• Q9UIM3

• Mouse Gene Id：
• 56299

• Mouse Swiss Prot No：
• O35450

• Rat Gene Id：
• 406168

• Rat Swiss Prot No：
• Q6MG81

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human FKBPL. AA range:251-300

• Specificity：
• FKBPL Polyclonal Antibody detects endogenous levels of FKBPL protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• FKBPL;DIR1;NG7;FK506-binding protein-like;WAF-1/CIP1 stabilizing protein 39;WISp39

• Observed Band(KD)：
• 38kD

• Background：
• The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008],

• Function：
• function:May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 TPR repeats.,subunit:Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90.,tissue specificity:Ubiquitously expressed with higher levels in testis.,

• Subcellular Location：
• endoplasmic reticulum membrane,cytosol,

• Expression：
• Ubiquitously expressed with higher levels in testis.

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