Fibulin-2 Polyclonal Antibody

    • Catalog No.:YT1707
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • Fibulin-2
      • Gene Name:
      • FBLN2
      • Protein Name:
      • Fibulin-2
      • Human Gene Id:
      • 2199
      • Human Swiss Prot No:
      • P98095
      • Mouse Swiss Prot No:
      • P37889
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human FBLN2. AA range:241-290
      • Specificity:
      • Fibulin-2 Polyclonal Antibody detects endogenous levels of Fibulin-2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • FBLN2;Fibulin-2;FIBL-2
      • Observed Band(KD):
      • 130kD
      • Background:
      • This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
      • Function:
      • developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,
      • Subcellular Location:
      • Secreted, extracellular space, extracellular matrix.
      • Expression:
      • Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.
      • Products Images
      • Western Blot analysis of various cells using Fibulin-2 Polyclonal Antibody diluted at 1:500
      • Immunofluorescence analysis of A549 cells, using FBLN2 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using FBLN2 Antibody. The picture on the right is blocked with the synthesized peptide.