FDC-SP Polyclonal Antibody
- Catalog No.:YT1687
- Applications:IHC;IF;ELISA
- Reactivity:Human
- Target:
- FDC-SP
- Gene Name:
- FDCSP
- Protein Name:
- Follicular dendritic cell secreted peptide
- Human Gene Id:
- 260436
- Human Swiss Prot No:
- Q8NFU4
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human FDC-SP. AA range: 26-75
- Specificity:
- FDC-SP Polyclonal Antibody detects endogenous levels of FDC-SP protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- FDCSP;C4orf7;Follicular dendritic cell secreted peptide;FDC secreted protein;FDC-SP
- Molecular Weight(Da):
- 10kD
- Background:
- This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion. [provided by RefSeq, Dec 2011],
- Function:
- function:Can bind to the surface of B-lymphoma cells, but not T-lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.,tissue specificity:Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon.,
- Subcellular Location:
- Secreted.
- Expression:
- Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).