• Target：
• ETL

• Gene Name：
• ELTD1

• Protein Name：
• EGF latrophilin and seven transmembrane domain-containing protein 1

• Human Gene Id：
• 64123

• Human Swiss Prot No：
• Q9HBW9

• Mouse Swiss Prot No：
• Q923X1

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human ELTD1. AA range:251-300

• Specificity：
• ETL Polyclonal Antibody detects endogenous levels of ETL protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ELTD1;ETL;EGF; latrophilin and seven transmembrane domain-containing protein 1;EGF-TM7-latrophilin-related protein;ETL protein

• Observed Band(KD)：
• 77kD

• Background：
• developmental stage:Up-regulated in the adult heart.,domain:The transmembrane domain is not required for cleavage, but it is required for dimer formation.,function:Could be involved in cardiac development.,PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 2 EGF-like domains.,subunit:Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface.,tissue specificity:Mainly expressed in smooth muscle.,

• Function：
• developmental stage:Up-regulated in the adult heart.,domain:The transmembrane domain is not required for cleavage, but it is required for dimer formation.,function:Could be involved in cardiac development.,PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 2 EGF-like domains.,subunit:Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface.,tissue specificity:Mainly expressed in smooth muscle.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Detected in the majority of epithelial cells in tumor and normal tissues. Expressed also in human umbilical vein endothelial cells.

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