EphA10 Polyclonal Antibody
- Catalog No.:YT1574
- Applications:WB;ELISA
- Reactivity:Human;Mouse
- Target:
- EphA10
- Gene Name:
- EPHA10
- Protein Name:
- Ephrin type-A receptor 10
- Human Gene Id:
- 284656
- Human Swiss Prot No:
- Q5JZY3
- Mouse Gene Id:
- 230735
- Mouse Swiss Prot No:
- Q8BYG9
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human EPHA10. AA range:431-480
- Specificity:
- EphA10 Polyclonal Antibody detects endogenous levels of EphA10 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- EPHA10;Ephrin type-A receptor 10
- Observed Band(KD):
- 110kD
- Background:
- Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008],
- Function:
- catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,domain:The protein kinase domain is predicted to be catalytically inactive.,function:Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Mainly expressed in testis.,
- Subcellular Location:
- [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
- Expression:
- Mainly expressed in testis.
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