Endomucin Polyclonal Antibody

    • Catalog No.:YT1557
    • Applications:IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Endomucin
      • Gene Name:
      • EMCN
      • Protein Name:
      • Endomucin
      • Human Swiss Prot No:
      • Q9ULC0
      • Mouse Swiss Prot No:
      • Q9R0H2
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human Mucin-14. AA range:201-250
      • Specificity:
      • Endomucin Polyclonal Antibody detects endogenous levels of Endomucin protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • EMCN;EMCN2;MUC14;Endomucin;Endomucin-2;Gastric cancer antigen Ga34;Mucin-14;MUC-14
      • Molecular Weight(Da):
      • 27kD
      • Background:
      • endomucin(EMCN) Homo sapiens EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008],
      • Function:
      • function:Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.,PTM:Highly O-glycosylated. Sialic acid-rich glycoprotein.,subcellular location:Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.,tissue specificity:Expressed in heart, kidney and lung.,
      • Subcellular Location:
      • [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.; [Isoform 2]: Secreted .
      • Expression:
      • Expressed in heart, kidney and lung.
      • Products Images
      • Immunofluorescence analysis of HepG2 cells, using Mucin-14 Antibody. The picture on the right is blocked with the synthesized peptide.