Endo G-L1 Polyclonal Antibody

    • Catalog No.：YT1555
    • Applications：WB;ELISA
    • Reactivity：Human;Mouse
      • Target：
      • Endo G-L1
      • Gene Name：
      • EXOG
      • Protein Name：
      • Nuclease EXOG mitochondrial
      • Human Gene Id：
      • 9941
      • Human Swiss Prot No：
      • Q9Y2C4
      • Mouse Swiss Prot No：
      • Q8C163
      • Immunogen：
      • The antiserum was produced against synthesized peptide derived from human ENDOGL1. AA range:171-220
      • Specificity：
      • Endo G-L1 Polyclonal Antibody detects endogenous levels of Endo G-L1 protein.
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name：
      • EXOG;ENDOGL1;ENDOGL2;ENGL;Nuclease EXOG; mitochondrial;Endonuclease G-like 1;Endo G-like 1
      • Observed Band(KD)：
      • 41kD
      • Background：
      • This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009],
      • Function：
      • cofactor:Divalent metal cations.,function:Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity.,miscellaneous:The active site contains 1 hydrated divalent metal cation that has only 1 direct interaction with the protein; all other interactions are via water molecules.,similarity:Belongs to the DNA/RNA non-specific endonuclease family.,subunit:Homodimer.,tissue specificity:Ubiquitous.,
      • Subcellular Location：
      • Mitochondrion inner membrane .
      • Expression：
      • Ubiquitous.
      • Products Images
      • Western Blot analysis of various cells using Endo G-L1 Polyclonal Antibody
      • Western blot analysis of lysates from HUVEC, HT-29, and HepG2 cells, using ENDOGL1 Antibody. The lane on the right is blocked with the synthesized peptide.

      Attributes

      • Code：
      • YT1555
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2024-11-25
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