EMR1 Polyclonal Antibody

    • Catalog No.:YT1544
    • Applications:WB;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • EMR1
      • Gene Name:
      • EMR1
      • Protein Name:
      • EGF-like module-containing mucin-like hormone receptor-like 1
      • Human Gene Id:
      • 2015
      • Human Swiss Prot No:
      • Q14246
      • Mouse Swiss Prot No:
      • Q61549
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human EMR1. AA range:818-867
      • Specificity:
      • EMR1 Polyclonal Antibody detects endogenous levels of EMR1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • EMR1;TM7LN3;EGF-like module-containing mucin-like hormone receptor-like 1;EGF-like module receptor 1;EMR1 hormone receptor
      • Observed Band(KD):
      • 98kD
      • Background:
      • This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
      • Function:
      • alternative products:Comment=Additional isoforms seem to exist,function:Could be involved in cell-cell interactions.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 6 EGF-like domains.,tissue specificity:Wide expression; increased levels in peripheral blood mononuclear cells.,
      • Subcellular Location:
      • Cell membrane ; Multi-pass membrane protein .
      • Expression:
      • Expression is restricted to eosinophils.
      • Products Images
      • Western Blot analysis of Jurkat cells using EMR1 Polyclonal Antibody
      • Western blot analysis of lysates from Jurkat cells, using EMR1 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HUVECcells using EMR1 antibody.