• Target：
• EF-Tu

• Gene Name：
• TUFM

• Protein Name：
• Elongation factor Tu mitochondrial

• Human Gene Id：
• 7284

• Human Swiss Prot No：
• P49411

• Mouse Gene Id：
• 233870

• Mouse Swiss Prot No：
• Q8BFR5

• Rat Gene Id：
• 293481

• Rat Swiss Prot No：
• P85834

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TUFM. AA range:301-350

• Specificity：
• EF-Tu Polyclonal Antibody detects endogenous levels of EF-Tu protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TUFM;Elongation factor Tu; mitochondrial;EF-Tu;P43

• Observed Band(KD)：
• 50kD

• Background：
• This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008],

• Function：
• disease:Defects in TUFM are the cause of combined oxidative phosphorylation deficiency type 4 (COXPD4) [MIM:610678]. COXPD4 is characterized by neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes.,function:This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.,similarity:Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.,

• Subcellular Location：
• Mitochondrion .

• Expression：
• Brain,Cajal-Retzius cell,Heart,Kidney,Liver,Lung,Placenta,P

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