• Target：
• EAT-2

• Fields：
• >>Natural killer cell mediated cytotoxicity

• Gene Name：
• SH2D1B

• Protein Name：
• SH2 domain-containing protein 1B

• Human Gene Id：
• 117157

• Human Swiss Prot No：
• O14796

• Mouse Swiss Prot No：
• O35324

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human SH2D1B. AA range:71-120

• Specificity：
• EAT-2 Polyclonal Antibody detects endogenous levels of EAT-2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SH2D1B;EAT2;SH2 domain-containing protein 1B;EWS/FLI1-activated transcript 2;EAT-2

• Molecular Weight(Da)：
• 15kD

• Background：
• By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008],

• Function：
• function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells.,similarity:Contains 1 SH2 domain.,subunit:Binds to the phosphorylated receptors CD84, CD150, CD229 and CD244. Does not bind to non-phosphorylated CD150.,

• Subcellular Location：
• intracellular,cytosol,

• Expression：
• Leukocyte,Lung,Spleen,

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