DREG Polyclonal Antibody
- Catalog No.:YT1413
- Applications:WB;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- DREG
- Gene Name:
- GPR126
- Protein Name:
- G-protein coupled receptor 126
- Human Gene Id:
- 57211
- Human Swiss Prot No:
- Q86SQ4
- Mouse Gene Id:
- 215798
- Mouse Swiss Prot No:
- Q6F3F9
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GPR126. AA range:1091-1140
- Specificity:
- DREG Polyclonal Antibody detects endogenous levels of DREG protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- GPR126;DREG;VIGR;G-protein coupled receptor 126;Developmentally regulated G-protein-coupled receptor;Vascular inducible G protein-coupled receptor
- Observed Band(KD):
- 140kD
- Background:
- This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009],
- Function:
- function:Orphan receptor.,polymorphism:Genetic variations in GPR126 influences stature as a quantitative trait (STQTL) [MIM:606255]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 1 pentaxin domain.,
- Subcellular Location:
- Cell membrane ; Multi-pass membrane protein . Detected on the cell surface of activated but not resting umbilical vein. .
- Expression:
- Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using DREG Polyclonal Antibody
- Immunofluorescence analysis of HUVEC cells, using GPR126 Antibody. The picture on the right is blocked with the synthesized peptide.