DBC-1 Polyclonal Antibody

    • Catalog No.:YT1294
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • DBC1
      • Gene Name:
      • KIAA1967
      • Protein Name:
      • DBIRD complex subunit KIAA1967
      • Human Swiss Prot No:
      • Q8N163
      • Mouse Swiss Prot No:
      • Q8VDP4
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human KIAA1967. AA range:431-480
      • Specificity:
      • DBC-1 Polyclonal Antibody detects endogenous levels of DBC-1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • KIAA1967;DBC1;DBIRD complex subunit KIAA1967;Deleted in breast cancer gene 1 protein;DBC-1;DBC.1;p30 DBC
      • Observed Band(KD):
      • 102kD
      • Background:
      • tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
      • Function:
      • tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
      • Subcellular Location:
      • Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Recruited to chromatin, post-UV irradiation. Sequestered to the cytoplasm in the presence of MCC. Translocated to the cytoplasm during UV-induced apoptosis. .
      • Expression:
      • Expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, using KIAA1967 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).