CYP2A6V2 Polyclonal Antibody
- Catalog No.：YT1206
- Applications：WB;IHC;IF;ELISA
- Reactivity：Human;Rat;Mouse;
- Target：
- CYP2A6V2
- Gene Name：
- CYP2A6V2
- Protein Name：
- Cytochrome P450
- Human Gene Id：
- 1548
- Human Swiss Prot No：
- Q13120
- Immunogen：
- Synthesized peptide derived from the Internal region of human CYP2A6V2.
- Specificity：
- CYP2A6V2 Polyclonal Antibody detects endogenous levels of CYP2A6V2 protein.
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Polyclonal, Rabbit,IgG
- Dilution：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
- Purification：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Observed Band(KD)：
- 56kD
- Background：
- This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.
- Function：
- oxidation reduction,
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- Antibody-FAQs
- Products Images
- Western Blot analysis of L929 cells using CYP2A6V2 Polyclonal Antibody diluted at 1:2000
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
