• Target：
• CROT

• Fields：
• >>Peroxisome

• Gene Name：
• CROT

• Protein Name：
• Peroxisomal carnitine O-octanoyltransferase

• Human Gene Id：
• 54677

• Human Swiss Prot No：
• Q9UKG9

• Mouse Gene Id：
• 74114

• Mouse Swiss Prot No：
• Q9DC50

• Rat Gene Id：
• 83842

• Rat Swiss Prot No：
• P11466

• Immunogen：
• Synthesized peptide derived from CROT . at AA range: 190-270

• Specificity：
• CROT Polyclonal Antibody detects endogenous levels of CROT protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CROT;COT;Peroxisomal carnitine O-octanoyltransferase;COT

• Observed Band(KD)：
• 72kD

• Background：
• This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009],

• Function：
• catalytic activity:Octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine.,function:Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the carnitine/choline acetyltransferase family.,subunit:Monomer.,

• Subcellular Location：
• Peroxisome .

• Expression：
• Brain,Skin,

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