CRBP-III Polyclonal Antibody

    • Catalog No.:YT1095
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • CRBP-III
      • Gene Name:
      • RBP5
      • Protein Name:
      • Retinol-binding protein 5
      • Human Swiss Prot No:
      • P82980
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CRBP III. AA range:10-59
      • Specificity:
      • CRBP-III Polyclonal Antibody detects endogenous levels of CRBP-III protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • RBP5;Retinol-binding protein 5;Cellular retinol-binding protein III;CRBP-III;HRBPiso
      • Molecular Weight(Da):
      • 16kD
      • Background:
      • retinol binding protein 5(RBP5) Homo sapiens The protein encoded by this gene is a cellular retinol-binding protein expressed highly in kidney and liver. Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates. [provided by RefSeq, Jul 2016],
      • Function:
      • domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Intracellular transport of retinol.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).,
      • Subcellular Location:
      • Cytoplasm .
      • Expression:
      • Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).
      • Products Images
      • Immunofluorescence analysis of LOVO cells, using CRBP III Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CRBP III Antibody. The picture on the right is blocked with the synthesized peptide.