• Target：
• COX7a2/3

• Gene Name：
• COX7A2/COX7A2P2

• Protein Name：
• Cytochrome c oxidase subunit 7A2/3 mitochondrial

• Human Gene Id：
• 1347

• Human Swiss Prot No：
• O60397/P14406

• Mouse Gene Id：
• 12866

• Rat Gene Id：
• 29507

• Rat Swiss Prot No：
• P35171

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human COX7S/A2. AA range:1-50

• Specificity：
• COX7a2/3 Polyclonal Antibody detects endogenous levels of COX7a2/3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• COX7A2P2;COX7A3;COX7AL2;COX7AP2;Putative cytochrome c oxidase subunit 7A3; mitochondrial;Cytochrome c oxidase subunit VIIa 3;COX7A2;COX7AL;Cytochrome c oxidase subunit 7A2, mitochondrial;Cytochrome c oxidase subunit VIIa-liver/hear

• Observed Band(KD)：
• 12kD

• Background：
• Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.

• Subcellular Location：
• Mitochondrion inner membrane .

The nature compound dehydrocrenatidine exerts potent antihepatocellular carcinoma by destroying mitochondrial complexes in vitro and in vivo 2022 Feb 02. WB Human

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