• Target：
• COX5a

• Fields：
• >>Oxidative phosphorylation;>>Metabolic pathways;>>Cardiac muscle contraction;>>Thermogenesis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy

• Gene Name：
• COX5A

• Protein Name：
• Cytochrome c oxidase subunit 5A mitochondrial

• Human Gene Id：
• 9377

• Human Swiss Prot No：
• P20674

• Mouse Gene Id：
• 12858

• Mouse Swiss Prot No：
• P12787

• Rat Gene Id：
• 252934

• Rat Swiss Prot No：
• P11240

• Immunogen：
• Synthesized peptide derived from COX5a . at AA range: 40-120

• Specificity：
• COX5a Polyclonal Antibody detects endogenous levels of COX5a protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• COX5A;Cytochrome c oxidase subunit 5A; mitochondrial;Cytochrome c oxidase polypeptide Va

• Observed Band(KD)：
• 17kD

• Background：
• Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008],

• Function：
• function:This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase subunit 5A family.,

• Subcellular Location：
• Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .

• Expression：
• Brain,Heart,Liver,

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