Connexin 37 Polyclonal Antibody

    • Catalog No.:YT1043
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Connexin 37
      • Gene Name:
      • GJA4
      • Protein Name:
      • Gap junction alpha-4 protein
      • Human Gene Id:
      • 2701
      • Human Swiss Prot No:
      • P35212
      • Mouse Swiss Prot No:
      • P28235
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human GJA4. AA range:81-130
      • Specificity:
      • Connexin 37 Polyclonal Antibody detects endogenous levels of Connexin 37 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • GJA4;Gap junction alpha-4 protein;Connexin-37;Cx37
      • Observed Band(KD):
      • 37kD
      • Background:
      • This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008],
      • Function:
      • function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.,
      • Subcellular Location:
      • Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
      • Expression:
      • Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, using GJA4 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from 293 cells using GJA4 antibody.