Connexin 37 Polyclonal Antibody
- Catalog No.:YT1043
- Applications:WB;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- Connexin 37
- Gene Name:
- GJA4
- Protein Name:
- Gap junction alpha-4 protein
- Human Gene Id:
- 2701
- Human Swiss Prot No:
- P35212
- Mouse Gene Id:
- 14612
- Mouse Swiss Prot No:
- P28235
- Rat Gene Id:
- 25655
- Rat Swiss Prot No:
- Q03190
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GJA4. AA range:81-130
- Specificity:
- Connexin 37 Polyclonal Antibody detects endogenous levels of Connexin 37 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- GJA4;Gap junction alpha-4 protein;Connexin-37;Cx37
- Observed Band(KD):
- 37kD
- Background:
- This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008],
- Function:
- function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.,
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
- Expression:
- Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from Jurkat cells, using GJA4 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from 293 cells using GJA4 antibody.