• Target：
• Connexin 31.3

• Gene Name：
• GJC3

• Protein Name：
• Gap junction gamma-3 protein

• Human Gene Id：
• 349149

• Human Swiss Prot No：
• Q8NFK1

• Mouse Swiss Prot No：
• Q921C1

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GJC3. AA range:151-200

• Specificity：
• Connexin 31.3 Polyclonal Antibody detects endogenous levels of Connexin 31.3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GJC3;GJE1;Gap junction gamma-3 protein;Connexin-30.2;Cx30.2;Connexin-31.3;Cx31.3;Gap junction epsilon-1 protein

• Observed Band(KD)：
• 28kD

• Background：
• This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010],

• Function：
• function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Gamma-type subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038 expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .

• Expression：
• CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.

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