COL14A1 Polyclonal Antibody

    • Catalog No.:YT1012
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • COL14A1
      • Fields:
      • >>Protein digestion and absorption
      • Gene Name:
      • COL14A1
      • Protein Name:
      • Collagen alpha-1(XIV) chain
      • Human Gene Id:
      • 7373
      • Human Swiss Prot No:
      • Q05707
      • Mouse Swiss Prot No:
      • Q80X19
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human N-ternal Collagen XIV alpha1. AA range:71-120
      • Specificity:
      • COL14A1 Polyclonal Antibody detects endogenous levels of COL14A1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • COL14A1;UND;Collagen alpha-1(XIV) chain;Undulin
      • Molecular Weight(Da):
      • 194kD
      • Background:
      • This gene encodes the alpha chain of type XIV collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XIV collagen interacts with the fibril surface and is involved in the regulation of fibrillogenesis. [provided by RefSeq, Jan 2013],
      • Function:
      • function:Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors.,PTM:Lysines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in all cases and bind carbohydrates.,PTM:May contain numerous cysteine residues involved in inter- and intramolecular disulfide bonding.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:
      • Subcellular Location:
      • Secreted, extracellular space, extracellular matrix .
      • Expression:
      • Brain,Liver,Muscle,PNS,Testis,
      • Products Images
      • Immunofluorescence analysis of HeLa cells, using Collagen XIV alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human heart tissue, using Collagen XIV alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.