CNT2 Polyclonal Antibody

    • Catalog No.:YT1004
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • CNT2
      • Gene Name:
      • SLC28A2
      • Protein Name:
      • Sodium/nucleoside cotransporter 2
      • Human Gene Id:
      • 9153
      • Human Swiss Prot No:
      • O43868
      • Mouse Swiss Prot No:
      • O88627
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SLC28A2. AA range:371-420
      • Specificity:
      • CNT2 Polyclonal Antibody detects endogenous levels of CNT2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SLC28A2;CNT2;Sodium/nucleoside cotransporter 2;Concentrative nucleoside transporter 2;CNT 2;hCNT2;Na(+)/nucleoside cotransporter 2;Sodium-coupled nucleoside transporter 2;Sodium/purine nucleoside co-transporter;SPNT;Solute carrier
      • Observed Band(KD):
      • 65kD
      • Background:
      • enzyme regulation:Inhibited by formycin B.,function:Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.,similarity:Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.,tissue specificity:Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.,
      • Function:
      • enzyme regulation:Inhibited by formycin B.,function:Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.,similarity:Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.,tissue specificity:Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.,
      • Subcellular Location:
      • Membrane ; Multi-pass membrane protein .
      • Expression:
      • Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain (PubMed:9435697). Weak expression in lung (PubMed:9435697).
      • Products Images
      • Western Blot analysis of various cells using CNT2 Polyclonal Antibody
      • Western Blot analysis of 3T3 cells using CNT2 Polyclonal Antibody
      • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SLC28A2 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from Jurkat cells, using SLC28A2 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HepG2 cells using SLC28A2 antibody.