• Target：
• CNG-2

• Fields：
• >>cAMP signaling pathway;>>Olfactory transduction

• Gene Name：
• CNGA2

• Protein Name：
• Cyclic nucleotide-gated olfactory channel

• Human Gene Id：
• 1260

• Human Swiss Prot No：
• Q16280

• Mouse Gene Id：
• 12789

• Mouse Swiss Prot No：
• Q62398

• Rat Gene Id：
• 25411

• Rat Swiss Prot No：
• Q00195

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human CNGA2. AA range:391-440

• Specificity：
• CNG-2 Polyclonal Antibody detects endogenous levels of CNG-2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CNGA2;CNCA;CNCA1;CNCG2;Cyclic nucleotide-gated olfactory channel;Cyclic nucleotide-gated cation channel 2;Cyclic nucleotide-gated channel alpha-2;CNG channel alpha-2;CNG-2;CNG2

• Observed Band(KD)：
• 83kD

• Background：
• The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. [provided by RefSeq, Jan 2010],

• Function：
• function:Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.,similarity:Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.,similarity:Contains 1 cyclic nucleotide-binding domain.,

• Subcellular Location：
• Membrane; Multi-pass membrane protein.

• Expression：
• Testis,

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