CIP29 Polyclonal Antibody

    • Catalog No.:YT0930
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • CIP29
      • Gene Name:
      • SARNP
      • Protein Name:
      • SAP domain-containing ribonucleoprotein
      • Human Swiss Prot No:
      • P82979
      • Mouse Swiss Prot No:
      • Q9D1J3
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human HCC1. AA range:147-196
      • Specificity:
      • CIP29 Polyclonal Antibody detects endogenous levels of CIP29 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SARNP;HCC1;HSPC316;SAP domain-containing ribonucleoprotein;Cytokine-induced protein of 29 kDa;Nuclear protein Hcc-1;Proliferation-associated cytokine-inducible protein CIP29
      • Observed Band(KD):
      • 30kD
      • Background:
      • This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
      • Function:
      • transcription, regulation of transcription, DNA-dependent, regulation of translation, posttranscriptional regulation of gene expression, regulation of cellular protein metabolic process, regulation of transcription, regulation of RNA metabolic process,
      • Subcellular Location:
      • Nucleus. Nucleus speckle.
      • Expression:
      • Low expression in spleen, liver, pancreas, testis, thymus, heart, and kidney. Increased levels are seen in hepatocellular carcinoma and pancreatic adenocarcinoma.
      • Products Images
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HCC1 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from mouse liver, using HCC1 Antibody. The lane on the right is blocked with the synthesized peptide.