• Target：
• CELSR3

• Gene Name：
• CELSR3

• Protein Name：
• Cadherin EGF LAG seven-pass G-type receptor 3

• Human Gene Id：
• 1951

• Human Swiss Prot No：
• Q9NYQ7

• Mouse Swiss Prot No：
• Q91ZI0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human CELSR3. AA range:91-140

• Specificity：
• CDHF11 Polyclonal Antibody detects endogenous levels of CDHF11 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CELSR3;CDHF11;EGFL1;FMI1;KIAA0812;MEGF2;Cadherin EGF LAG seven-pass G-type receptor 3;Cadherin family member 11;Epidermal growth factor-like protein 1;EGF-like protein 1;Flamingo homolog 1;hFmi1;Multiple epidermal growth factor-

• Molecular Weight(Da)：
• 358kD

• Background：
• This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013],

• Function：
• function:Does not seem to be involved in anion transport.,function:Receptor that may have an important role in cell/cell signaling during nervous system formation.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.,similarity:Contains 1 GPS domain.,similarity:Contains 1 laminin EGF-like domain.,similarity:Contains 1 STAS domain.,similarity:Contains 2 laminin G-like domains.,similarity:Contains 8 EGF-like domains.,similarity:Contains 9 cadherin domains.,tissue specificity:Ubiquitous. Highest levels in kidney and pancreas. Lower expression in heart, skeletal muscle, liver and placenta. Also found in lung and brain.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Brain,Cord blood,Duodenum,Epithelium,Kidney,Uterus,

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