CD70 Polyclonal Antibody

    • Catalog No.:YT0774
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • CD70
      • Fields:
      • >>Cytokine-cytokine receptor interaction
      • Gene Name:
      • CD70
      • Protein Name:
      • CD70 antigen
      • Human Gene Id:
      • 970
      • Human Swiss Prot No:
      • P32970
      • Mouse Swiss Prot No:
      • O55237
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CD70. AA range:68-117
      • Specificity:
      • CD70 Polyclonal Antibody detects endogenous levels of CD70 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CD70;CD27L;CD27LG;TNFSF7;CD70 antigen;CD27 ligand;CD27-L;Tumor necrosis factor ligand superfamily member 7;CD antigen CD70
      • Observed Band(KD):
      • 30kD
      • Background:
      • The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,
      • Subcellular Location:
      • Membrane ; Single-pass type II membrane protein .
      • Expression:
      • B-cell,Kidney,
      • Products Images
      • Western Blot analysis of various cells using CD70 Polyclonal Antibody diluted at 1:2000
      • Western blot analysis of the lysates from Jurkat cells using CD70 antibody.