CD2BP2 Polyclonal Antibody

    • Catalog No.:YT0746
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Monkey
      • Target:
      • CD2BP2
      • Gene Name:
      • CD2BP2
      • Protein Name:
      • CD2 antigen cytoplasmic tail-binding protein 2
      • Human Swiss Prot No:
      • O95400
      • Mouse Swiss Prot No:
      • Q9CWK3
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150
      • Specificity:
      • CD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CD2BP2;KIAA1178;CD2 antigen cytoplasmic tail-binding protein 2;CD2 cytoplasmic domain-binding protein 2;CD2 tail-binding protein 2
      • Observed Band(KD):
      • 50kD
      • Background:
      • This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],
      • Function:
      • similarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain.,
      • Subcellular Location:
      • Cytoplasm. Nucleus. Predominantly nuclear.
      • Expression:
      • Aorta,Brain,Epithelium,Liver,Lung,
      • Products Images
      • Western Blot analysis of various cells using CD2BP2 Polyclonal Antibody diluted at 1:1000
      • Western blot analysis of lysates from COS7 cells, using CD2 Tail-binding Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HeLa cells using CD2 Tail-binding antibody.