• Target：
• CCK

• Fields：
• >>Neuroactive ligand-receptor interaction;>>Insulin secretion;>>Pancreatic secretion

• Gene Name：
• CCK

• Protein Name：
• Cholecystokinin

• Human Gene Id：
• 885

• Human Swiss Prot No：
• P06307

• Mouse Gene Id：
• 12424

• Mouse Swiss Prot No：
• P09240

• Rat Gene Id：
• 25298

• Rat Swiss Prot No：
• P01355

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human CCK. AA range:46-95

• Specificity：
• CCK Polyclonal Antibody detects endogenous levels of CCK protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CCK;Cholecystokinin;CCK

• Molecular Weight(Da)：
• 13kD

• Background：
• This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015],

• Function：
• function:This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.,online information:Cholecystokinin entry,PTM:The precursor is cleaved by proteases to produce a number of active cholecystokinins.,similarity:Belongs to the gastrin/cholecystokinin family.,subunit:Binds to CCK-A receptors in the pancreas and CCK-B receptors in the brain.,

• Subcellular Location：
• Secreted.

• Expression：
• Brain,Pancreas,

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