Casein Kinase I α1/1L Polyclonal Antibody

    • Catalog No.:YT0642
    • Applications:IHC;IF;WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Casein Kinase I α1/1L
      • Fields:
      • >>Wnt signaling pathway;>>Hedgehog signaling pathway;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer
      • Gene Name:
      • CSNK1A1/CSNK1A1L
      • Protein Name:
      • Casein kinase I isoform alpha/Casein kinase I isoform alpha-like
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CKI-alpha1/L. AA range:141-190
      • Specificity:
      • Casein Kinase I α1/1L Polyclonal Antibody detects endogenous levels of Casein Kinase I α1/1L protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CSNK1A1L;Casein kinase I isoform alpha-like;CKI-alpha-like;CK1;CSNK1A1;Casein kinase I isoform alpha;CKI-alpha;CK1
      • Observed Band(KD):
      • 30kD
      • Background:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,
      • Function:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,
      • Subcellular Location:
      • Cytoplasm .
      • Expression:
      • Testis,
      • Products Images
      • Immunofluorescence analysis of A549 cells, using CKI-alpha1/L Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CKI-alpha1/L Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night