CaMKIβ Polyclonal Antibody
- Catalog No.:YT0629
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- CaMKIβ
- Gene Name:
- PNCK
- Protein Name:
- Calcium/calmodulin-dependent protein kinase type 1B
- Human Gene Id:
- 139728
- Human Swiss Prot No:
- Q6P2M8
- Mouse Gene Id:
- 93843
- Mouse Swiss Prot No:
- Q9QYK9
- Rat Gene Id:
- 29660
- Rat Swiss Prot No:
- O70150
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CaMK1-beta. AA range:161-210
- Specificity:
- CaMKIβ Polyclonal Antibody detects endogenous levels of CaMKIβ protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- PNCK;Calcium/calmodulin-dependent protein kinase type 1B;CaM kinase I beta;CaM kinase IB;CaM-KI beta;CaMKI-beta;Pregnancy up-regulated non-ubiquitously-expressed CaM kinase
- Observed Band(KD):
- 38kD
- Background:
- PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008],
- Function:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by Ca(2+)/calmodulin.,function:Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1.,PTM:Phosphorylated by CAMKK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,
- Subcellular Location:
- Cytoplasm . Nucleus .
- Expression:
- Brain,Liver,Placenta,Thalamus,
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- Antibody-FAQs
- Products Images
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CaMK1-beta Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from LOVO cells, treated with H2O2 100uM 30', using CaMK1-beta Antibody. The lane on the right is blocked with the synthesized peptide.