Cadherin-7 Polyclonal Antibody
- Catalog No.:YT0602
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- Cadherin-7
- Gene Name:
- CDH7
- Protein Name:
- Cadherin-7
- Human Gene Id:
- 1005
- Human Swiss Prot No:
- Q9ULB5
- Mouse Gene Id:
- 241201
- Mouse Swiss Prot No:
- Q8BM92
- Rat Gene Id:
- 29162
- Rat Swiss Prot No:
- Q5DWV2
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CDH7. AA range:651-700
- Specificity:
- Cadherin-7 Polyclonal Antibody detects endogenous levels of Cadherin-7 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CDH7;CDH7L1;Cadherin-7
- Observed Band(KD):
- 87kD
- Background:
- This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18. [provided by RefSeq, May 2016],
- Function:
- function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,
- Subcellular Location:
- Cell membrane; Single-pass type I membrane protein.
- Expression:
- Brain,
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using Cadherin-7 Polyclonal Antibody diluted at 1:1000
- Western blot analysis of lysates from A549 cells, using CDH7 Antibody. The lane on the right is blocked with the synthesized peptide.