Cadherin-7 Polyclonal Antibody

    • Catalog No.:YT0602
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Cadherin-7
      • Gene Name:
      • CDH7
      • Protein Name:
      • Cadherin-7
      • Human Gene Id:
      • 1005
      • Human Swiss Prot No:
      • Q9ULB5
      • Mouse Swiss Prot No:
      • Q8BM92
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CDH7. AA range:651-700
      • Specificity:
      • Cadherin-7 Polyclonal Antibody detects endogenous levels of Cadherin-7 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CDH7;CDH7L1;Cadherin-7
      • Observed Band(KD):
      • 87kD
      • Background:
      • This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18. [provided by RefSeq, May 2016],
      • Function:
      • function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,
      • Subcellular Location:
      • Cell membrane; Single-pass type I membrane protein.
      • Expression:
      • Brain,
      • Products Images
      • Western Blot analysis of various cells using Cadherin-7 Polyclonal Antibody diluted at 1:1000
      • Western blot analysis of lysates from A549 cells, using CDH7 Antibody. The lane on the right is blocked with the synthesized peptide.