• Target：
• C3aR

• Fields：
• >>Neuroactive ligand-receptor interaction;>>Complement and coagulation cascades;>>Alcoholic liver disease;>>Staphylococcus aureus infection;>>Coronavirus disease - COVID-19

• Gene Name：
• C3AR1

• Protein Name：
• C3a anaphylatoxin chemotactic receptor

• Human Gene Id：
• 719

• Human Swiss Prot No：
• Q16581

• Mouse Swiss Prot No：
• O09047

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human C3AR1. AA range:175-224

• Specificity：
• C3aR Polyclonal Antibody detects endogenous levels of C3aR protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• C3AR1;AZ3B;C3R1;HNFAG09;C3a anaphylatoxin chemotactic receptor;C3AR;C3a-R

• Molecular Weight(Da)：
• 54kD

• Background：
• C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016],

• Function：
• function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.

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