BCA3 Polyclonal Antibody

    • Catalog No.:YT0462
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • BCA3
      • Gene Name:
      • AKIP1
      • Protein Name:
      • A-kinase-interacting protein 1
      • Human Swiss Prot No:
      • Q9NQ31
      • Mouse Swiss Prot No:
      • Q9JJR5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human BCA3. AA range:111-160
      • Specificity:
      • BCA3 Polyclonal Antibody detects endogenous levels of BCA3 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • AKIP1;BCA3;C11orf17;A-kinase-interacting protein 1;Breast cancer-associated gene 3 protein;PKA-interacting protein;Proline-rich protein BCA3
      • Observed Band(KD):
      • 26kD
      • Background:
      • This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
      • Function:
      • subcellular location:Locates to punctate spots.,subunit:Interacts with PRKACA.,tissue specificity:Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.,
      • Subcellular Location:
      • Nucleus . Locates to punctate spots.
      • Expression:
      • Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.
      • Products Images
      • Western Blot analysis of various cells using BCA3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
      • Immunohistochemistry analysis of paraffin-embedded human heart tissue, using BCA3 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from Jurkat cells, using BCA3 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HepG2 cells using BCA3 antibody.