BACH1 Polyclonal Antibody

    • Catalog No.:YT0431
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • BACH1
      • Gene Name:
      • BACH1
      • Protein Name:
      • Transcription regulator protein BACH1
      • Human Gene Id:
      • 571
      • Human Swiss Prot No:
      • O14867
      • Mouse Swiss Prot No:
      • P97302
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human BACH1. AA range:131-180
      • Specificity:
      • BACH1 Polyclonal Antibody detects endogenous levels of BACH1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • BACH1;Transcription regulator protein BACH1;BTB and CNC homolog 1;HA2303
      • Observed Band(KD):
      • 100kD
      • Background:
      • This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009],
      • Function:
      • function:Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Epithelium,Placenta,Trachea,
      • Products Images
      • Western Blot analysis of various cells using BACH1 Polyclonal Antibody
      • Immunofluorescence analysis of HeLa cells, using BACH1 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HepG2 cells, using BACH1 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).