• Target：
• ATF5

• Gene Name：
• ATF5

• Protein Name：
• Cyclic AMP-dependent transcription factor ATF-5

• Human Gene Id：
• 22809

• Human Swiss Prot No：
• Q9Y2D1

• Mouse Gene Id：
• 107503

• Mouse Swiss Prot No：
• O70191

• Rat Gene Id：
• 282840

• Rat Swiss Prot No：
• Q6P788

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human ATF5. AA range:221-270

• Specificity：
• ATF-5 Polyclonal Antibody detects endogenous levels of ATF-5 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ATF5;ATFX;Cyclic AMP-dependent transcription factor ATF-5;cAMP-dependent transcription factor ATF-5;Activating transcription factor 5;Transcription factor ATFx

• Observed Band(KD)：
• 31kD

• Background：
• function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,

• Function：
• function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,

• Subcellular Location：
• Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. .

• Expression：
• Widely expressed with higher expression levels in liver.

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