AR-α1D Polyclonal Antibody
- Catalog No.:YT0357
- Applications:IHC;IF;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- AR-α1D
- Fields:
- >>Calcium signaling pathway;>>cGMP-PKG signaling pathway;>>Neuroactive ligand-receptor interaction;>>Adrenergic signaling in cardiomyocytes;>>Vascular smooth muscle contraction;>>Salivary secretion
- Gene Name:
- ADRA1D
- Protein Name:
- Alpha-1D adrenergic receptor
- Human Gene Id:
- 146
- Human Swiss Prot No:
- P25100
- Mouse Swiss Prot No:
- P97714
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ADRA1D. AA range:451-500
- Specificity:
- AR-α1D Polyclonal Antibody detects endogenous levels of AR-α1D protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- ADRA1D;ADRA1A;Alpha-1D adrenergic receptor;Alpha-1A adrenergic receptor;Alpha-1D adrenoreceptor;Alpha-1D adrenoceptor;Alpha-adrenergic receptor 1a
- Molecular Weight(Da):
- 60kD
- Background:
- Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008],
- Function:
- function:This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.,similarity:Belongs to the G-protein coupled receptor 1 family.,
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
- Expression:
- Hippocampus,Placenta,Prostate,
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- Antibody-FAQs
- Products Images
- Immunofluorescence analysis of HeLa cells, using ADRA1D Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ADRA1D Antibody. The picture on the right is blocked with the synthesized peptide.