AR-α1D Polyclonal Antibody

    • Catalog No.:YT0357
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • AR-α1D
      • Fields:
      • >>Calcium signaling pathway;>>cGMP-PKG signaling pathway;>>Neuroactive ligand-receptor interaction;>>Adrenergic signaling in cardiomyocytes;>>Vascular smooth muscle contraction;>>Salivary secretion
      • Gene Name:
      • ADRA1D
      • Protein Name:
      • Alpha-1D adrenergic receptor
      • Human Gene Id:
      • 146
      • Human Swiss Prot No:
      • P25100
      • Mouse Swiss Prot No:
      • P97714
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human ADRA1D. AA range:451-500
      • Specificity:
      • AR-α1D Polyclonal Antibody detects endogenous levels of AR-α1D protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • ADRA1D;ADRA1A;Alpha-1D adrenergic receptor;Alpha-1A adrenergic receptor;Alpha-1D adrenoreceptor;Alpha-1D adrenoceptor;Alpha-adrenergic receptor 1a
      • Molecular Weight(Da):
      • 60kD
      • Background:
      • Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008],
      • Function:
      • function:This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.,similarity:Belongs to the G-protein coupled receptor 1 family.,
      • Subcellular Location:
      • Cell membrane; Multi-pass membrane protein.
      • Expression:
      • Hippocampus,Placenta,Prostate,
      • Products Images
      • Immunofluorescence analysis of HeLa cells, using ADRA1D Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ADRA1D Antibody. The picture on the right is blocked with the synthesized peptide.