AQP5 Polyclonal Antibody
- Catalog No.:YT0293
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- AQP5
- Fields:
- >>Salivary secretion
- Gene Name:
- AQP5
- Protein Name:
- Aquaporin-5
- Human Gene Id:
- 362
- Human Swiss Prot No:
- P55064
- Mouse Swiss Prot No:
- Q9WTY4
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human AQP5. AA range:194-243
- Specificity:
- AQP5 Polyclonal Antibody detects endogenous levels of AQP5 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- AQP5;Aquaporin-5;AQP-5
- Observed Band(KD):
- 35kD
- Background:
- Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008],
- Function:
- domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,
- Subcellular Location:
- Apical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane. .
- Expression:
- Detected in skin eccrine sweat glands, at the apical cell membrane and at intercellular canaliculi (at protein level).
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using AQP5 Polyclonal Antibody
- Immunohistochemistry analysis of AQP5 antibody in paraffin-embedded human lung carcinoma tissue.
- Western blot analysis of lysate from HUVECcells, using AQP5 antibody.