• Target：
• ApoL3

• Gene Name：
• APOL3

• Protein Name：
• Apolipoprotein L3

• Human Gene Id：
• 80833

• Human Swiss Prot No：
• O95236

• Immunogen：
• Synthesized peptide derived from ApoL3 . at AA range: 100-180

• Specificity：
• ApoL3 Polyclonal Antibody detects endogenous levels of ApoL3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• APOL3;Apolipoprotein L3;Apolipoprotein L-III;ApoL-III;TNF-inducible protein CG12-1;CG12_1

• Molecular Weight(Da)：
• 44kD

• Background：
• This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015],

• Function：
• function:May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.,induction:In vitro, is responsive to tumor necrosis factor.,similarity:Belongs to the apolipoprotein L family.,tissue specificity:Widely expressed; the highest levels are in prostate, lung and placenta; also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland; levels are low in brain, heart, fetal liver, pancreas and testis.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Widely expressed; the highest levels are in prostate, lung and placenta; also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland; levels are low in brain, heart, fetal liver, pancreas and testis.

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