• Target：
• AMPD2

• Fields：
• >>Purine metabolism;>>Metabolic pathways;>>Nucleotide metabolism

• Gene Name：
• AMPD2

• Protein Name：
• AMP deaminase 2

• Human Gene Id：
• 271

• Human Swiss Prot No：
• Q01433

• Mouse Gene Id：
• 109674

• Mouse Swiss Prot No：
• Q9DBT5

• Rat Gene Id：
• 362015

• Rat Swiss Prot No：
• Q02356

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human AMPD2. AA range:131-180

• Specificity：
• AMPD2 Polyclonal Antibody detects endogenous levels of AMPD2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• AMPD2;AMP deaminase 2;AMP deaminase isoform L

• Observed Band(KD)：
• 100kD

• Background：
• The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],

• Function：
• catalytic activity:AMP + H(2)O = IMP + NH(3).,function:AMP deaminase plays a critical role in energy metabolism.,pathway:Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.,similarity:Belongs to the adenosine and AMP deaminases family.,subunit:Homotetramer.,tissue specificity:Three isoforms are present in mammals: AMP deaminase 1 is the predominant form in skeletal muscle; AMP deaminase 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; AMP deaminase 3 is found in erythrocytes.,

• Subcellular Location：
• cytosol,

• Expression：
• Highly expressed in cerebellum.

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