• Target：
• AKR1CL2

• Gene Name：
• AKR1E2

• Protein Name：
• 1,5-anhydro-D-fructose reductase

• Human Gene Id：
• 83592

• Human Swiss Prot No：
• Q96JD6

• Mouse Swiss Prot No：
• Q9DCT1

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human AKR1CL2. AA range:141-190

• Specificity：
• AKR1CL2 Polyclonal Antibody detects endogenous levels of AKR1CL2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• AKR1E2;AKR1CL2;AKRDC1;1;5-anhydro-D-fructose reductase;AF reductase;Aldo-keto reductase family 1 member C-like protein 2;Aldo-keto reductase family 1 member E2;LoopADR;Testis-specific protein;hTSP

• Observed Band(KD)：
• 37kD

• Background：
• The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

• Function：
• catalytic activity:1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.,function:Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones.,similarity:Belongs to the aldo/keto reductase family.,tissue specificity:Testis-specific.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078).

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