• Target：
• AKAP 14

• Gene Name：
• AKAP14

• Protein Name：
• A-kinase anchor protein 14

• Human Gene Id：
• 158798

• Human Swiss Prot No：
• Q86UN6

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human AKAP14. AA range:1-50

• Specificity：
• AKAP 14 Polyclonal Antibody detects endogenous levels of AKAP 14 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• AKAP14;AKAP28;A-kinase anchor protein 14;AKAP-14;A-kinase anchor protein 28 kDa;AKAP 28;Protein kinase A-anchoring protein 14;PRKA14

• Observed Band(KD)：
• 23kD

• Background：
• The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

• Function：
• caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Binds to type II regulatory subunits of protein kinase A and anchors/targets them.,subunit:Binds to type II regulatory subunits (RII).,tissue specificity:Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.

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